Table 3 O2 kinetic elimination Michaelis-Menten parameters plus diffusion (converted from Davidson et al. [28], their Table 1)
From: A physiologically-based flow network model for hepatic drug elimination III: 2D/3D DLA lobule models
Parameter | Characteristic unit | STARS unit |
|---|---|---|
Maximum Rate v max | 352 μM/min | 6.34 × 10−6 mole fraction/min |
Half Saturation Constant K m | 6.24 μM | 1.12 × 10−7 mole fraction |
Linear Rate v max/K m | 56.4 min−1 | 56.4 min−1 |
Sinusoid Effective Diffusion | 3.0 × 10−9 m2/sec | 1.8 × 10−3 cm2/min |
Tissue Effective Diffusion | 2.0 × 10−9 m2/sec | 1.2 × 10−3 cm2/min |