Fig. 1
Dynamics of SHIV-KS661 and -#64 infection in HSC-F cells. HSC-F cells were inoculated with SHIV-KS661 or -#64 at two different multiplicities of infection (i.e., 2.0 × 10−4 or 2.0 × 10−5 TCID50 per cell) in cell cultures. Panels show the time-course of experimental data (log scale) for the concentration of Nef-negative and Nef-positive HSC-F cells and the viral loads consisting of RNA copies/ml and TCID50/ml for SHIV-KS661 and -#64, respectively. The shadow regions correspond to 95% posterior predictive intervals, the solid curves give the best-fit solution (mean) for Eqs. (5,6,7 and 8) to the time-course dataset. All data for each strain were fitted simultaneously