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Table 2 Fitted initial (t = 0) values for the in vitro experiment

From: A highly pathogenic simian/human immunodeficiency virus effectively produces infectious virions compared with a less pathogenic virus in cell culture

Variable

Unit

Fitted initial value at MOI of

SHIV-KS661

SHIV-#64

2 × 10−4

2 × 10−5

2 × 10−4

2 × 10−5

T j (0)

cells/ml

6.31 × 106a

6.31 × 106a

6.24 × 106 a

6.24 × 106a

I j (0)

cells/ml

17.9 (5.41–38.8)b

0.802 (0.358–1.47)b

40.3 (5.78–1.22 × 102) b

8.71 (1.08–29.4)b

V RNAj (0)

RNA copies/ml

2.15 × 105 (2.58 × 104–8.30 × 105)a

2.45 × 104 (3.45 × 103–9.98 × 104)a

1.66 × 107 (1.09 × 106–8.25 × 107)a

4.90 × 105 (6.94 × 104–1.82 × 106)a

V 50j (0)

TCID50/ml

0.0729 (6.94 × 10−4–0.432)a

0.0304 (2.16 × 10−3–0.121)a

0.124 (5.11 × 10−4–0.609)a

0.0468 (9.71 × 10−3–0.124)a

  1. a T j (0) are fixed
  2. bbest fit value (95% CI)