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Table 2 Dependence of agrochemical mixture effect predictions on Hill parameters

From: Theory of synergistic effects: Hill-type response surfaces as ‘null-interaction’ models for mixtures

 

Slope γ=1

Slope γ variable

Ligand

X 50 a

RMSEb

X 50 a

Slope

RMSEb

Atrazine

0.057

 

0.059

0.96

 

Alachlor

0.082

 

0.076

1.45

 

Atrazine + Alachlor

 

9

  

9

Aldrin

0.008

 

0.010

2.20

 

Dieldrin

0.004

 

0.005

1.95

 

Aldrin + Dieldrin

 

10

  

8

Oxadixyl

18

 

19

1.37

 

Mancozeb

294

 

293

0.99

 

Oxadixyl + Mancozeb

 

25

  

26

  1. All pesticides are assumed to achieve individual maximum effects of 100%. The magnitude of the deviations of mixture predictions from the experimental data is an indication of synergistic effects
  2. a LC 50 (in kg/ha) for herbicides, LD 50 (in g a.i./100 ml kerosene solution) for insecticides, EC 50 (in mg/l) for fungicides;
  3. broot-mean-square error of efficacy prediction for mixture