From: A mathematical model for histamine synthesis, release, and control in varicosities
Coefficient | Value | Explanation |
---|---|---|
a 1 | 12 | HA leakage from the cytosol to the extracellular space |
a 2 | 5 | HA release per action potential |
a 3 | 12 | HA leakage from glia to the extracellular space |
a 4 | .001 | HA removal from the extracellular space |
a 5 | .25 | Strength of stabilization of blood HT near 100 μM |
a 6 | 2.5 | From cHT to HTpool |
a 7 | 1 | From HTpool to cHT |
a 8 | 1 | other uses of HT remove HT |
a 9 | 4.32 | Bound autoreceptors produce G ∗ |
a 10 | 1.296 | T ∗ facilitates the reversion of G ∗ to G |
a 11 | 14.4 | G ∗ produces T ∗ |
a 12 | 25.92 | decay coefficient of T ∗ |
a 13 | 432 | eHA binds to autoreceptors |
a 14 | 1440 | eHA dissociates from autoreceptors |