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Table 3 Posterior estimates of the MR for humans

From: Application of Bayesian evidence synthesis to modelling the effect of ketogenic therapy on survival of high grade glioma patients

 

KD

KD+

CR

CR+

Original study estimates

1.41 (0.61-2.21)

1.26 (0.77-1.75)

NA

1.75 (1.22-2.28)

Skeptical prior SP1

1.29 (0.58-2.81)

1.39 (0.65-2.98)

1.51 (0.57-3.98)

1.69 (0.68-4.22)

Skeptical prior SP2

1.29 (0.68-2.45)

1.39 (0.73-2.59)

1.50 (0.70-3.21)

1.54 (0.73-3.29)

Fundamentalist skeptical FSP

1.29 (0.65-2.55)

1.36 (0.68-2.65)

1.49 (0.65-3.6)

1.47 (0.64-3.33)

Relational priors RP1

1.33 (0.63-2.76)

1.40 (0.71-2.76)

1.50 (0.64-3.48)

1.65 (0.76-3.63)

Relational priors RP2

1.33 (0.63-2.77)

1.40 (0.72-2.78)

1.50 (0.64-3.48)

1.65 (0.75-3.64)

Relational priors RP3

1.33 (0.63-2.74)

1.41 (0.71-2.77)

1.50 (0.63-3.47)

1.65 (0.76-3.64)

Mechanistic prior MP1

1.24 (0.65-2.34)

1.40 (0.73-2.64)

1.43 (0.66-3.04)

1.67 (0.78-3.58)

Mechanistic prior MP2

1.36 (0.73-2.49)

1.48 (0.87-2.53)

1.39 (0.73-2.57)

1.51 (0.87-2.63)

Enthusiastic prior EP

1.45 (0.81-2.51)

1.50 (0.86-2.58)

1.68 (0.88-3.13)

1.59 (0.80-3.22)

Enthusiastic prior EP + MP1

1.40 (0.78-2.42)

1.53 (0.86-2.65)

1.62 (0.84-3.04)

1.74 (0.86-3.59)

Enthusiastic prior EP + MP2

1.53 (0.91-2.49)

1.56 (0.97-2.50)

1.56 (0.91-2.57)

1.58 (0.97-2.61)

  1. The numbers give the median and 95% credible interval obtained with different prior distributions
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Theoretical Biology and Medical Modelling

ISSN: 1742-4682