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Fig. 3 | Theoretical Biology and Medical Modelling

Fig. 3

From: Identification of influential proteins in the classical retinoic acid signaling pathway

Fig. 3

Sensitivity ranking of the model parameters. The model output was set to the time integral of the transcription rate of the GOI within 24 h after adding 1 nM of RA to the model. Blue bars indicate first-order sensitivity indices, while red bars represent total-effect sensitivity indices. The error bars show the bootstrap confidence intervals (95% confidence intervals) of the mean values [36]. Detailed parameter description is provided in Additional file 1

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