Fig. 3
From: Identification of influential proteins in the classical retinoic acid signaling pathway
Sensitivity ranking of the model parameters. The model output was set to the time integral of the transcription rate of the GOI within 24Â h after adding 1Â nM of RA to the model. Blue bars indicate first-order sensitivity indices, while red bars represent total-effect sensitivity indices. The error bars show the bootstrap confidence intervals (95% confidence intervals) of the mean values [36]. Detailed parameter description is provided in Additional file 1