Theoretical Biology and Medical Modelling

Table 1 Best predictive model based on DNN

From: Model based on GA and DNN for prediction of mRNA-Smad7 expression regulated by miRNAs in breast cancer

Generation	Individual	miRNAs count	Validation	Hidden layers	MSE	R²
23	17	45	Hold-out	42:63	0.003877	0.9275
19	16	53	Hold-out	42:63	0.004425	0.9224
21	28	53	Hold-out	42:63	0.003982	0.9174
21	6	52	Hold-out	42:63	0.003612	0.9167
17	36	52	Hold-out	42:63	0.003668	0.9139
18	20	54	Hold-out	42:63	0.004021	0.9138
22	7	50	Hold-out	42:63	0.004431	0.9137
20	8	55	Hold-out	46:61	0.004826	0.9128
17	5	53	Hold-out	42:63	0.004176	0.9119
19	25	55	Hold-out	42:63	0.004045	0.9112

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