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Table 5 Nervous system model parameters

From: Mathematical modeling of septic shock based on clinical data

Parameter

Value

Description

Sources

af,max

1.3175

Maximum value of sympathetic nerve activity af

Estimated

ar,max

8.6993

Maximum value of sympathetic nerve activity ar

Estimated

aV,max

0.9443

Maximum value of sympathetic nerve activity aV

Estimated

af,min

0.1896

Minimum value of sympathetic nerve activity af

Estimated

ar,min

2.6996

Minimum value of sympathetic nerve activity ar

Estimated

aV,min

0.8206

Minimum value of sympathetic nerve activity aV

Estimated

k γ

3.0 × 10−5

Sympathetic nerve effect coefficient forγ

Estimated

a f0

0.680

Sympathetic nervous activity for f0

Estimated

a r0

0.549

Sympathetic nervous activity for r0

Estimated

a V0

0.0935

Sympathetic nervous activity for V0

Estimated

f 0

1.2beat/s

Normal value of heart rate f

Estimated by [16]

R s1,0

0.0113mmHg·s/ml

Normal value of arteriolar vascular resistance Rs1

Estimated by [16]

V usv,0

2.9 × 10−3ml

Normal value of venous unstressed blood bolume Vusv

Estimated by [16]

r 0

3.0μm

Normal value of arteriovascular radius r

Estimated by [17]

k f

1.01

Sympathetic nerve effect coefficient for f

Estimated

k r

8.2

Sympathetic nerve effect coefficient for r

Estimated

k V

1.0

Sympathetic nerve effect coefficient for Vusv

Estimated