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Fig. 3 | Theoretical Biology and Medical Modelling

Fig. 3

From: Effects of a high protein diet and liver disease in an in silico model of human ammonia metabolism

Fig. 3

Ammonia levels changed with dietary protein levels, liver cirrhosis, and CPS1 activity. a The steady state ammonia concentration in the blood increases with increased ammonia absorption due to increases in dietary protein (See Table 1) and decreased liver function. b When CPS1 activity is reduced by half, steady state ammonia levels are higher than those in an individual with normal enzyme activities. This effect increases with increased ammonia absorption due to increased dietary protein levels (See Table 1)

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