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Table 2 Parameter values used in nitrogen metabolism model

From: Effects of a high protein diet and liver disease in an in silico model of human ammonia metabolism

Parameter Name

Value

References

Blood Volume

6.59 La

 

Average Liver Mass

1561 g

[32]

Average Human Mass, Male

88.7 kg

[1]

Time Through Sinusoid

4.3 s

[33]

Initial Urea

5.5 mM

 

Initial Ammonia

0 μM

 

Initial Glutamine

0 mM

 

Recommended Daily Protein

71 g

[34]

  1. aBlood volume is about 5.2 L for a 70 kg individual [35]. The value used above was determined by assuming a linear relationship of blood volume with body mass for an individual weighing 88.7 kg. This is the volume of the blood compartment used to calculate metabolite concentrations
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Theoretical Biology and Medical Modelling

ISSN: 1742-4682