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Table 3 Parameter changes with altered protein intake and liver condition

From: Effects of a high protein diet and liver disease in an in silico model of human ammonia metabolism

Parameter Name Protein in Diet (g per day) Normal Enzyme Activity (mmoles/min) Enzyme Activity in Liver Cirrhosis (mmoles/min)
Urea ex 71 0.244 0.244
100 0.343 0.343
122 0.417 0.417
NH3 ex 71 0.004 0.004
100 0.008 0.008
122 0.012 0.012
NH3 abs 71 0.492 0.492
100 0.693 0.693
122 0.845 0.845
Vmax CPS1 71 8.05 5.64
100 8.47 5.93
122 8.78 6.146
Vmax GLUL No change with diet 12.3 2.46