Fig. 2

Model validation. Model simulations produced by the LGMM (blue lines), NLGMM (red lines) and the minimal model (black dashed lines) for the two different IVGTT’s (mean data and SEM illustrated by circles and error-bars) presented in Thomaseth et al. 2014 [17]. A, B and C shows the predictions for the insulin modified IVGTT, while D, E and F illustrates the results for the IVGTT with glucose infusion. A and D represent blood glucose concentration, B and E represent plasma insulin and C and F represent plasma glucagon concentration’