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Fig. 1 | Theoretical Biology and Medical Modelling

Fig. 1

From: UGM: a more stable procedure for large-scale multiple testing problems, new solutions to identify oncogene

Fig. 1

Relationship between P(i) and its frequency; P(i) and i are simu-lated data (10,000 genes). a. Frequency distribution of P(i); b. P(i) vs i. Note: Hypothesis testing has the following two characteristics. I). When H0 is true, the P value calculated from observed value is uniform distribution in (0, 1), i.e., P ~ U (0, 1). II). When H0 is false, the distribution of P value is uncertain. However according to the definition of P value can be known, this time P value is small. Usually the P value is less than 0.05, and tends to zero

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