Fig. 7From: Computational modeling of the effects of autophagy on amyloid-β peptide levelsAβ concentrations depending upon activities of three autophagy steps. The surfaces specify time-averaged intracellular Aβ concentration 〈CS3〉 (first row) and extracellular Aβ concentration 〈CES3〉 (second row) for basal parameter values; regions above and below the surfaces correspond to Aβ concentrations lower and higher than the basal values. The first and the second columns correspond to β/β(0) = 10 and β/β(0) = 100, respectively. Computations were performed with rl3/rl3(0) and rh3/rh3(0) varied in increments and the mixed cubic and quintic spline interpolation applied. On the surfaces in purple the Aβ concentrations display oscillations while oscillations are absent on the green surfacesBack to article page