From: The self-organization model reveals systematic characteristics of aging
Model | Profiles | Pathway | FDR |
---|---|---|---|
0–20 vs. 20–50 | methylation | negative regulation of cellular senescence (GO:2000773) | 0.0016 |
20–50 vs. 50–70 | methylation | negative regulation of viral process (GO:0048525) | 0.0005 |
50–70 vs. 70-survival | methylation | prostage gland morphogenesis (GO:0016578) branch elongation of an epithelium (GO:0060602) axis elongation (GO:0003401) | 0.0041 |
0–50 vs. 50-survival | methylation | histone deubiquitination (GO:0016578) | 0.003 |
0–20 vs. 20–50 | expression | response to electrical stimulus (GO:0051602) | 0.0324 |
20–50 vs. 50–70 | expression | fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540) alpha-linolenic acid metabolic process (GO:0036109) | 0.0014 |
50–70 vs. 70-survival | expression | progesterone metabolic process (GO:0042448) | 0.0028 |
0–50 vs. 50-survival | expression | purinergic nucleotide receptor signaling pathway (GO:0035590) | 0.0012 |