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Table 1 Key variables used to adjust the system environment of the model

From: An agent-based model to investigate microbial initiation of Alzheimer’s via the olfactory system

Concentrations

 EBs of C. pneumoniae bacteria in outside environment

 Olfactory cells in olfactory epithelium

 Sustentacular cells in olfactory epithelium

 Mitral cells in olfactory bulb

 Microglia in olfactory bulb

 Neurons in olfactory cortex

 Microglia in olfactory cortex

 Neurons in hippocampus

 Microglia in hippocampus

Rates

 Olfactory cell recovery rate

C. pneumoniae chance of infection of olfactory cells

 Microglia repair distance

 Olfactory cell division

 Replication of reticulate bodies in endosome of hosts

 Infected cell lysis