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Fig. 2 | Theoretical Biology and Medical Modelling

Fig. 2

From: Simulation-based assessment of model selection criteria during the application of benchmark dose method to quantal response data

Fig. 2

Simulation-based assessment of model selection criteria using the benchmark dose (BMD) method. We used three different datasets, 1-aminoanthraquinone, 2-ethylhexyl vinyl ether, and acrylamide. For each dataset, unbiased estimates were obtained for the benchmark dose that was 10% of the benchmark response (BMD10) and the lower bound of the benchmark dose with response level at 10% (unbiased BMDL10). Random realizations for generating 1000 replicas of the experimental data were conducted and applied the BMD method with nine models for each replica, which generated 9000 different model fits that were evaluated

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