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Table 3 Estimated characteristic parameters of the antiviral drug combinations

From: Required concentration index quantifies effective drug combinations against hepatitis C virus infection

Drug

\( {IC}_{50}^{\mathrm{com}} \)

mcom

RCI95

genotype 1b

genotype 2a

genotype 1b

genotype 2a

genotype 1b

genotype 2a

SOF&DCV&VX

0.40

–

1.92

–

1.89

–

SOF&DCV&ASV

0.55

0.13

2.03

2.09

2.33

0.58

SOF&DCV&DAS

0.34

0.20

1.97

2.28

1.52

0.73

SOF&DCV&SMV

0.33

0.16

2.14

2.23

1.31

0.62

SOF&LDV&VX

0.45

–

1.90

–

2.12

–

SOF&LDV&ASV

0.46

0.33

1.88

2.88

2.21

0.95

SOF&LDV&DAS

0.35

0.26

1.88

2.49

1.66

0.90

SOF&LDV&SMV

0.26

0.35

1.90

3.04

1.21

0.98

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Theoretical Biology and Medical Modelling

ISSN: 1742-4682