Transition Rate λij | Baseline | Log-linear βij | Hazard exp(βij) | Time-varying viral load (VL) levels VLstates, k | ||||
---|---|---|---|---|---|---|---|---|
λij(CD4, 0) | VLstates, k | \( {P}_{VL(k)}^{\ast } \) | VLstates, k | \( {P}_{VL(k)}^{\ast } \) | State 1 | State 2 | State 3 | |
State 1 to 2 λ12 | 0.0192 | 0.1678 | 0.1739 | 1.0827 | 1.1899 | 0.0182 | 0.0161 | 0.02763 |
State 1 to 3 λ13 | 0.2856 | − 0.3505 | −1.8298 | 0.7044 | 0.1604 | 0.7431 | 0.4755 | 1.3939 |
State 1 to 5 λ15 | 0.0381 | 0.5612 | 0.5131 | 1.7528 | 1.6704 | 0.0245 | 0.0333 | 0.0535 |
State 2 to 1 λ21 | 0.0114 | − 0.6837 | 0.6186 | 0.5048 | 0.8563 | 0.0168 | 0.0068 | 0.0088 |
State 2 to 3 λ23 | 0.0404 | 0.4762 | 1.0791 | 1.6099 | 2.9419 | 0.0239 | 0.0261 | 0.0948 |
State 2 to 4 λ24 | 0.0086 | − 1.0434 | − 0.6853 | 0.3663 | 0.5039 | 0.0283 | 0.0067 | 0.0126 |
State 2 to 5 λ25 | 0.0551 | 0.5786 | −0.0711 | 1.7836 | 0.9314 | 0.0338 | 0.0729 | 0.0416 |
State 3 to 1 λ31 | 0.0062 | − 1.6657 | − 0.5138 | 0.1891 | 0.5982 | 0.0235 | 0.0055 | 0.0077 |
State 3 to 2 λ32 | 0.0036 | 0.2016 | −0.3475 | 1.2233 | 0.7064 | 0.0039 | 0.0032 | 0.0131 |
State 3 to 4 λ34 | 0.0079 | 0.1820 | 0.1034 | 1.1996 | 1.1089 | 0.0057 | 0.0069 | 0.0421 |
State 3 to 5 λ35 | 0.0195 | 0.2806 | −0.1784 | 1.3239 | 0.8366 | 0.0156 | 0.0217 | 0.0305 |