Transition Rate λij | Baseline | Log-linear βij | Hazard exp(βij) | Time-varying CD4 cell counts levels CD4states, k | ||||
---|---|---|---|---|---|---|---|---|
λij(VL, 0) | CD4states, k | \( {P}_{CD4(k)}^{\ast } \) | CD4states, k | \( {P}_{CD4(k)}^{\ast } \) | State 1 | State 2 | State 3 | |
State 1 to 2 λ12 | 0.0286 | 0.0434 | −0.3383 | 1.0443 | 0.713 | 0.0305 | 0.0321 | 0.0337 |
State 1 to 3 λ13 | 0.0025 | − 1.0072 | − 0.3336 | 0.3652 | 0.7163 | 0.0167 | 0.0059 | 0.0021 |
State 1 to 4 λ14 | 0.0082 | 0.0288 | 0.0247 | 1.0292 | 1.0243 | 0.0078 | 0.0081 | 0.0083 |
State 1 to 5 λ15 | 0.0159 | − 0.7155 | −1.1045 | 0.4889 | 0.3312 | 0.1774 | 0.0422 | 0.0206 |
State 2 to 1 λ21 | 0.0161 | − 0.3926 | − 0.2849 | 0.6762 | 0.7521 | 0.0351 | 0.0237 | 0.0161 |
State 2 to 3 λ23 | 0.0008 | 0.2065 | 0.6052 | 1.2293 | 1.8315 | 0.0004 | 0.0005 | 0.0006 |
State 2 to 4 λ24 | 0.0057 | 0.0725 | −0.2381 | 1.0752 | 0.7881 | 0.0056 | 0.0061 | 0.0066 |
State 2 to 5 λ25 | 0.0305 | − 0.7458 | − 0.9312 | 0.4744 | 0.3941 | 0.3372 | 0.0759 | 0.0361 |
State 3 to 1 λ31 | 0.0266 | − 0.9855 | −0.7571 | 0.3733 | 0.4691 | 0.1926 | 0.0728 | 0.0275 |
State 3 to 2 λ32 | 0.0035 | − 1.4092 | −2.8306 | 0.2443 | 0.0589 | 0.1359 | 0.0324 | 0.0077 |
State 3 to 4 λ34 | 0.0272 | − 0.0811 | 0.3475 | 0.9221 | 1.4155 | 0.0255 | 0.0237 | 0.0221 |
State 3 to 5 λ35 | 0.0343 | − 0.5176 | 0.0947 | 0.5959 | 1.0993 | 0.1273 | 0.0457 | 0.0273 |