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  1. Previously it has been shown that insulin-mediated tyrosine phosphorylation of myosin heavy chain is concomitant with enhanced association of C-terminal SRC kinase during skeletal muscle differentiation. We so...

    Authors: DF Harney, RK Butler and RJ Edwards

    Citation: Theoretical Biology and Medical Modelling 2005 2:12

    Content type: Research

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  2. The present paper describes a topological model of biofeedback. This model incorporates input from a sensory organ and a transduction phase mediated through catecholamine production in the feedback path. The t...

    Authors: Tapas K Basak, Suman Halder, Madona Kumar, Renu Sharma and Bijoylaxmi Midya

    Citation: Theoretical Biology and Medical Modelling 2005 2:11

    Content type: Research

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  3. The exact relationship between hormonal activity and prostate cancer(PCa) has not yet been clearly defined. One of the key hormones associated with PCa is testosterone(T). However, both in vitro and in vivo studi...

    Authors: A Edward Friedman

    Citation: Theoretical Biology and Medical Modelling 2005 2:10

    Content type: Research

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  4. Bone adapts to mechanical strain by rearranging the trabecular geometry and bone density. The common finite element methods used to simulate this adaptation have inconsistencies regarding material properties a...

    Authors: Zhengyuan Wang and Adrian Mondry

    Citation: Theoretical Biology and Medical Modelling 2005 2:6

    Content type: Research

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  5. Propagation of repolarization is a phenomenon that occurs in cardiac muscle. We wanted to test whether this phenomenon would also occur in our model of simulated action potentials (APs) of cardiac muscle (CM) ...

    Authors: Nicholas Sperelakis, Lakshminarayanan Ramasamy and Bijoy Kalloor

    Citation: Theoretical Biology and Medical Modelling 2005 2:5

    Content type: Research

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  6. Analysis of growth and division often involves measurements made on cell populations, which tend to average data. The value of single cell analysis needs to be appreciated, and models based on findings from si...

    Authors: JM Mitchison

    Citation: Theoretical Biology and Medical Modelling 2005 2:4

    Content type: Research

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  7. There is a substantial discrepancy between in vitro and in vivo experiments. The purpose of the present work was development of a theoretical framework to enable improved prediction of in vivo response from in vi...

    Authors: Ross Barnard and Konstantin G Gurevich

    Citation: Theoretical Biology and Medical Modelling 2005 2:3

    Content type: Research

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  8. Binding of a bacteria to a eukaryotic cell triggers a complex network of interactions in and between both cells. P. aeruginosa is a pathogen that causes acute and chronic lung infections by interacting with the p...

    Authors: Ekaterina Shelest and Edgar Wingender

    Citation: Theoretical Biology and Medical Modelling 2005 2:2

    Content type: Research

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  9. Ki-1 (CD30) antigen expression is not found on peripheral blood cells but its expression can be induced in vitro on T and B lymphocytes by viruses and lectins. Expression of CD30 in normal tissues is very limi...

    Authors: Demetrio Tamiolakis, John Venizelos, Maria Lambropoulou, Silva Nikolaidou, Sophia Bolioti, Maria Tsiapali, Dionysios Verettas, Panagiotis Tsikouras, Athanasios Chatzimichail and Nikolas Papadopoulos

    Citation: Theoretical Biology and Medical Modelling 2005 2:1

    Content type: Research

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  10. The relationship between body mass (M) and standard metabolic rate (B) among living organisms remains controversial, though it is widely accepted that in many cases B is approximately proportional to the three...

    Authors: Paul S Agutter and Denys N Wheatley

    Citation: Theoretical Biology and Medical Modelling 2004 1:13

    Content type: Review

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  11. In a recent publication it was claimed that cultured mammalian cells, in contrast to yeasts, maintain a constant size distribution in the population without a size checkpoint. This inference may be challengeable.

    Authors: Akos Sveiczer, Bela Novak and J Murdoch Mitchison

    Citation: Theoretical Biology and Medical Modelling 2004 1:12

    Content type: Commentary

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  12. The Bunyaviridae family of enveloped RNA viruses includes five genuses, orthobunyaviruses, hantaviruses, phleboviruses, nairoviruses and tospoviruses. It has not been determined which Bunyavirus protein mediat...

    Authors: Courtney E Garry and Robert F Garry

    Citation: Theoretical Biology and Medical Modelling 2004 1:10

    Content type: Research

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  13. In a previous study, a model was developed to investigate the release of luteinizing hormone (LH) from pituitary cells in response to a short pulse of gonadotropin-releasing hormone (GnRH). The model included:...

    Authors: Talitha M Washington, J Joseph Blum, Michael C Reed and P Michael Conn

    Citation: Theoretical Biology and Medical Modelling 2004 1:9

    Content type: Research

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  14. Dense time series of metabolite concentrations or of the expression patterns of proteins may be available in the near future as a result of the rapid development of novel, high-throughput experimental techniqu...

    Authors: Siren R Veflingstad, Jonas Almeida and Eberhard O Voit

    Citation: Theoretical Biology and Medical Modelling 2004 1:8

    Content type: Research

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  15. Human Immunodeficiency Virus (HIV) infection is a dynamic interaction of the pathogen and the host uniquely defined by the preference of the pathogen for a major component of the immune defense of the host. Si...

    Authors: Slobodan Tepic

    Citation: Theoretical Biology and Medical Modelling 2004 1:7

    Content type: Research

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  16. The key to a rational treatment of elementary Mendelian genetics, specifically to an understanding of the origin of dominant and recessive traits, lies in the facts that: (1) alleles of genes encode polypeptid...

    Authors: John W Porteous

    Citation: Theoretical Biology and Medical Modelling 2004 1:6

    Content type: Research

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  17. Integral membrane proteins are the primary targets of novel drugs but are largely without solved structures. As a consequence, hydrophobic moment plot methodology is often used to identify putative transmembrane

    Authors: James Wallace, Onkabetse A Daman, Frederick Harris and David A Phoenix

    Citation: Theoretical Biology and Medical Modelling 2004 1:5

    Content type: Research

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  18. The present article corrects common textbook accounts of Mendel's experiments by re-establishing what he wrote and how he accounted for his observations. It notes the long-established tests for the validity of...

    Authors: John W Porteous

    Citation: Theoretical Biology and Medical Modelling 2004 1:4

    Content type: Research

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  19. The phenomenon of switch-like response to graded input signal is the theme involved in various signaling pathways in living systems. Positive feedback loops or double negative feedback loops embedded with nonl...

    Authors: Lopamudra Giri, Vivek K Mutalik and KV Venkatesh

    Citation: Theoretical Biology and Medical Modelling 2004 1:2

    Content type: Research

    Published on:

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