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Page 8 of 13

  1. The concept of disaster surge has arisen in recent years to describe the phenomenon of severely increased demands on healthcare systems resulting from catastrophic mass casualty events (MCEs) such as natural d...

    Authors: Erik R Barthel, James R Pierce, Catherine J Goodhue, Henri R Ford, Tracy C Grikscheit and Jeffrey S Upperman
    Citation: Theoretical Biology and Medical Modelling 2011 8:38
  2. We review grounding issues that influence the scientific usefulness of any biomedical multiscale model (MSM). Groundings are the collection of units, dimensions, and/or objects to which a variable or model con...

    Authors: C Anthony Hunt, Glen EP Ropella, Tai ning Lam and Andrew D Gewitz
    Citation: Theoretical Biology and Medical Modelling 2011 8:35
  3. In nature, bacteria often exist as biofilms. Biofilms are communities of microorganisms attached to a surface. It is clear that biofilm-grown cells harbor properties remarkably distinct from planktonic cells. ...

    Authors: Andrew A Shalá, Silvia Restrepo and Andrés F González Barrios
    Citation: Theoretical Biology and Medical Modelling 2011 8:34
  4. There is a growing realization that alterations in host-pathogen interactions (HPI) can generate disease phenotypes without pathogen invasion. The gut represents a prime region where such HPI can arise and man...

    Authors: John B Seal, John C Alverdy, Olga Zaborina and Gary An
    Citation: Theoretical Biology and Medical Modelling 2011 8:33
  5. It was recently shown that the treatment effect of an antibody can be described by a consolidated parameter which includes the reaction rates of the receptor-toxin-antibody kinetics and the relative concentrat...

    Authors: Vladas Skakauskas, Pranas Katauskis and Alex Skvortsov
    Citation: Theoretical Biology and Medical Modelling 2011 8:32
  6. Arsenic in drinking water, a major health hazard to millions of people in South and East Asia and in other parts of the world, is ingested primarily as trivalent inorganic arsenic (iAs), which then undergoes h...

    Authors: Sean D Lawley, Molly Cinderella, Megan N Hall, Mary V Gamble, H Frederik Nijhout and Michael C Reed
    Citation: Theoretical Biology and Medical Modelling 2011 8:31
  7. This paper discusses the properties of cancer cells from a new perspective based on an analogy with phase transitions in physical systems. Similarities in terms of instabilities and attractor states are outlin...

    Authors: Paul CW Davies, Lloyd Demetrius and Jack A Tuszynski
    Citation: Theoretical Biology and Medical Modelling 2011 8:30
  8. Upon the addition of protons to an aqueous solution, a component of the H+ load will be bound i.e. buffered. In an aqueous solution containing a triprotic acid, H+ can be bound to three different states of the ac...

    Authors: Minhtri K Nguyen, Liyo Kao and Ira Kurtz
    Citation: Theoretical Biology and Medical Modelling 2011 8:29
  9. Personalised cancer therapy, such as that used for bronchial carcinoma (BC), requires treatment to be adjusted to the patient's status. Individual risk for progression is estimated from clinical and molecular-...

    Authors: Wolfgang Kössler, Anette Fiebeler, Arnulf Willms, Tina ElAidi, Bernd Klosterhalfen and Uwe Klinge
    Citation: Theoretical Biology and Medical Modelling 2011 8:28
  10. Most information on the dose-response of radiation-induced cancer is derived from data on the A-bomb survivors. Since, for radiation protection purposes, the dose span of main interest is between zero and one ...

    Authors: Uwe Schneider, Marcin Sumila and Judith Robotka
    Citation: Theoretical Biology and Medical Modelling 2011 8:27
  11. Texture analysis (TA) of histological images has recently received attention as an automated method of characterizing liver fibrosis. The colored staining methods used to identify different tissue components r...

    Authors: Doaa Mahmoud-Ghoneim
    Citation: Theoretical Biology and Medical Modelling 2011 8:25
  12. Fingerprints represent a particular characteristic for each individual. Characteristic patterns are also formed on the palms of the hands and soles of the feet. Their origin and development is still unknown bu...

    Authors: Diego A Garzón-Alvarado and Angelica M Ramírez Martinez
    Citation: Theoretical Biology and Medical Modelling 2011 8:24
  13. Herpes simplex type II (HSV-2) is a member of the family herpesviridae. Human infection with this double stranded linear DNA virus causes genital ulcerative disease and existing treatment options only serve to re...

    Authors: Misaki Wayengera
    Citation: Theoretical Biology and Medical Modelling 2011 8:23
  14. In this paper we provide a review of selected mathematical ideas that can help us better understand the boundary between living and non-living systems. We focus on group theory and abstract algebra applied to ...

    Authors: Edward A Rietman, Robert L Karp and Jack A Tuszynski
    Citation: Theoretical Biology and Medical Modelling 2011 8:21
  15. 7D-cadherins like LI-cadherin are cell adhesion molecules and represent exceptional members of the cadherin superfamily. Although LI-cadherin was shown to act as a functional Ca2+-dependent adhesion molecule, lin...

    Authors: Mareike Ahl, Agnes Weth, Sebastian Walcher and Werner Baumgartner
    Citation: Theoretical Biology and Medical Modelling 2011 8:18
  16. Proteins in any solution with a pH value that differs from their isoelectric point exert both an electric Donnan effect (DE) and colloid osmotic pressure. While the former alters the distribution of ions, the ...

    Authors: Sven Kurbel
    Citation: Theoretical Biology and Medical Modelling 2011 8:16
  17. Mitotic chromosome motions have recently been correlated with electrostatic forces, but a lingering "molecular cell biology" paradigm persists, proposing binding and release proteins or molecular geometries fo...

    Authors: Daniel H Shain and L John Gagliardi
    Citation: Theoretical Biology and Medical Modelling 2011 8:15
  18. Mathematical modeling can be employed to overcome the practical difficulty of isolating the mechanisms responsible for clinical heart failure in the setting of normal left ventricular ejection fraction (HFNEF)...

    Authors: Chuan Luo, Deepa Ramachandran, David L Ware, Tony S Ma and John W Clark Jr
    Citation: Theoretical Biology and Medical Modelling 2011 8:14
  19. Bioinformatics can be used to predict protein function, leading to an understanding of cellular activities, and equally-weighted protein-protein interactions (PPI) are normally used to predict such protein fun...

    Authors: Khaled S Ahmed, Nahed H Saloma and Yasser M Kadah
    Citation: Theoretical Biology and Medical Modelling 2011 8:11
  20. Avida is a computer program that performs evolution experiments with digital organisms. Previous work has used the program to study the evolutionary origin of complex features, namely logic operations, but has...

    Authors: Chase W Nelson and John C Sanford
    Citation: Theoretical Biology and Medical Modelling 2011 8:9
  21. Biofilms are microbial communities encased in a layer of extracellular polymeric substances (EPS). The EPS matrix provides several functional purposes for the biofilm, such as protecting bacteria from environm...

    Authors: Mallory R Frederick, Christina Kuttler, Burkhard A Hense and Hermann J Eberl
    Citation: Theoretical Biology and Medical Modelling 2011 8:8
  22. We investigated an algorithmic approach to modelling angiogenesis controlled by vascular endothelial growth factor (VEGF), the anti-angiogenic soluble VEGF receptor 1 (sVEGFR-1) and adenosine (Ado). We explore...

    Authors: Francisco Azuaje, Frédérique Léonard, Magali Rolland-Turner, Yvan Devaux and Daniel R Wagner
    Citation: Theoretical Biology and Medical Modelling 2011 8:7
  23. Mathematical modeling of angiogenesis has been gaining momentum as a means to shed new light on the biological complexity underlying blood vessel growth. A variety of computational models have been developed, ...

    Authors: Gang Liu, Amina A Qutub, Prakash Vempati, Feilim Mac Gabhann and Aleksander S Popel
    Citation: Theoretical Biology and Medical Modelling 2011 8:6
  24. Fatty acid biosynthesis of Mycobacterium tuberculosis was analyzed using graph theory and influential (impacting) proteins were identified. The graphs (digraphs) representing this biological network provide infor...

    Authors: Veeky Baths, Utpal Roy and Tarkeshwar Singh
    Citation: Theoretical Biology and Medical Modelling 2011 8:5
  25. Successfully evaluating pathologists' acumen could be very useful in improving the concordance of their calls on histopathologic variables. We are proposing a new method to estimate the reviewers' acumen based...

    Authors: Wei Zhao, James M Boyett, Mehmet Kocak, David W Ellison and Yanan Wu
    Citation: Theoretical Biology and Medical Modelling 2011 8:3
  26. While many pandemic preparedness plans have promoted disease control effort to lower and delay an epidemic peak, analytical methods for determining the required control effort and making statistical inferences...

    Authors: Ryosuke Omori and Hiroshi Nishiura
    Citation: Theoretical Biology and Medical Modelling 2011 8:2
  27. The immune system behaves like a complex, dynamic network with interacting elements including leukocytes, cytokines, and chemokines. While the immune system is broadly distributed, leukocytes must communicate ...

    Authors: Virginia A Folcik, Gordon Broderick, Shunmugam Mohan, Brian Block, Chirantan Ekbote, John Doolittle, Marc Khoury, Luke Davis and Clay B Marsh
    Citation: Theoretical Biology and Medical Modelling 2011 8:1
  28. We have previously suggested that the stimulatory effect of a weak immune reaction on tumor growth may be necessary for the growth of incipient tumors. In the present paper, we enlarge upon and extend that ide...

    Authors: Richmond T Prehn and Liisa M Prehn
    Citation: Theoretical Biology and Medical Modelling 2010 7:45
  29. Recent experimental studies suggest that tissue stem cell pools are composed of functionally diverse clones. Metapopulation models in ecology concentrate on collections of populations and their role in stabili...

    Authors: David P Tuck and Willard Miranker
    Citation: Theoretical Biology and Medical Modelling 2010 7:44
  30. The past thirty-five years have seen an intense search for the molecular mechanisms underlying calcium-induced calcium-release (CICR) in cardiac myocytes, with voltage clamp (VC) studies being the leading tool...

    Authors: Abhilash Krishna, Liang Sun, Miguel Valderrábano, Philip T Palade and John W Clark Jr
    Citation: Theoretical Biology and Medical Modelling 2010 7:43
  31. Plague is a re-emerging disease and its pneumonic form is a high priority bio-terrorist threat. Epidemiologists have previously analysed historical outbreaks of pneumonic plague to better understand the dynami...

    Authors: Joseph R Egan
    Citation: Theoretical Biology and Medical Modelling 2010 7:39
  32. Ultrasound elasticity imaging provides biomechanical and elastic properties of vascular tissue, with the potential to distinguish between tissue motion and tissue strain. To validate the ability of ultrasound ...

    Authors: Prashant Patel, Rohan Biswas, Daewoo Park, Thomas J Cichonski, Michael S Richards, Jonathan M Rubin, Sem Phan, James Hamilton and William F Weitzel
    Citation: Theoretical Biology and Medical Modelling 2010 7:36
  33. One of the goals of computational immunology is to facilitate the study of infectious diseases. Dynamic modeling is a powerful tool to integrate empirical data from independent sources, make novel predictions,...

    Authors: Juilee Thakar, Mary Poss, Réka Albert, Gráinne H Long and Ranran Zhang
    Citation: Theoretical Biology and Medical Modelling 2010 7:35
  34. The potential of using skin as an alternative path for systemically administering active drugs has attracted considerable interest, since the creation of novel drugs capable of diffusing through the skin would...

    Authors: Tatiana T Marquez-Lago, Diana M Allen and Jenifer Thewalt
    Citation: Theoretical Biology and Medical Modelling 2010 7:33