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Page 9 of 13

  1. Recently, the network paradigm, an application of graph theory to biology, has proven to be a powerful approach to gaining insights into biological complexity, and has catalyzed the advancement of systems biol...

    Authors: Paolo Tieri, Andrea Grignolio, Alexey Zaikin, Michele Mishto, Daniel Remondini, Gastone C Castellani and Claudio Franceschi
    Citation: Theoretical Biology and Medical Modelling 2010 7:32
  2. Both prophylaxis and treatment of venous thromboembolism (VTE: deep venous thrombosis (DVT) and pulmonary emboli (PE)) with anticoagulants are associated with significant risks of major and fatal hemorrhage. A...

    Authors: David K Cundiff, Paul S Agutter, P Colm Malone and John C Pezzullo
    Citation: Theoretical Biology and Medical Modelling 2010 7:31
  3. Living things come in all shapes and sizes, from bacteria, plants, and animals to humans. Knowledge about the genetic mechanisms for biological shape has far-reaching implications for a range spectrum of scien...

    Authors: Guifang Fu, Arthur Berg, Kiranmoy Das, Jiahan LI, Runze LI and Rongling Wu
    Citation: Theoretical Biology and Medical Modelling 2010 7:28
  4. There is still not an appealing and testable model to explain how single-celled organisms, usually following fusion of male and female gametes, proceed to grow and evolve into multi-cellular, complexly differe...

    Authors: Edward C Elson
    Citation: Theoretical Biology and Medical Modelling 2010 7:26
  5. Analyze an approach to distributing transperineal prostate biopsy cores that yields data on the volume of a tumor that might be present when the biopsy is negative, and also increases detection efficiency.

    Authors: Gordon R Kepner and Jeremy V Kepner
    Citation: Theoretical Biology and Medical Modelling 2010 7:23
  6. Alzheimer's disease, known to be associated with the gradual loss of memory, is characterized by low concentration of acetylcholine in the hippocampus and cortex part of the brain. Inhibition of acetylcholines...

    Authors: Zaheer Ul-Haq, Waqasuddin Khan, Saima Kalsoom and Farzana L Ansari
    Citation: Theoretical Biology and Medical Modelling 2010 7:22
  7. In this paper we consider two approaches to examining the complex dynamics of conjoint aging-cancer cellular systems undergoing chemotherapeutic intervention. In particular, we focus on the effect of cells gro...

    Authors: Mitra S Feizabadi and Tarynn M Witten
    Citation: Theoretical Biology and Medical Modelling 2010 7:21
  8. According to the hypothesis explored in this paper, native aggregation is genetically controlled (programmed) reversible aggregation that occurs when interacting proteins form new temporary structures through ...

    Authors: Vladimir V Matveev
    Citation: Theoretical Biology and Medical Modelling 2010 7:19
  9. ChIP-Seq is a powerful tool for identifying the interaction between genomic regulators and their bound DNAs, especially for locating transcription factor binding sites. However, high cost and high rate of fals...

    Authors: Song Wu, Jianmin Wang, Wei Zhao, Stanley Pounds and Cheng Cheng
    Citation: Theoretical Biology and Medical Modelling 2010 7:18
  10. Humans are routinely and concurrently exposed to multiple toxic chemicals, including various metals and organics, often at levels that can cause adverse and potentially synergistic effects. However, toxicokine...

    Authors: Alan F Sasso, Sastry S Isukapalli and Panos G Georgopoulos
    Citation: Theoretical Biology and Medical Modelling 2010 7:17
  11. Glucocorticoids (GC) represent the core treatment modality for many inflammatory diseases. Its mode of action is difficult to grasp, not least because it includes direct modulation of many components of the ex...

    Authors: Uwe Klinge, Nicolette Farman and Anette Fiebeler
    Citation: Theoretical Biology and Medical Modelling 2010 7:16
  12. Although the prognosis for Lupus Nephritis (LN) has dramatically improved with aggressive immunosuppressive therapies, these drugs carry significant side effects. To improve the effectiveness of these drugs, b...

    Authors: Paula Budu-Grajdeanu, Richard C Schugart, Avner Friedman, Daniel J Birmingham and Brad H Rovin
    Citation: Theoretical Biology and Medical Modelling 2010 7:14
  13. In many areas of medical research, a bivariate analysis is desirable because it simultaneously tests two response variables that are of equal interest and importance in two populations. Several parametric and ...

    Authors: Hamed Tabesh, S MT Ayatollahi and Mina Towhidi
    Citation: Theoretical Biology and Medical Modelling 2010 7:13
  14. Experimental reality in molecular and cell biology, as revealed by advanced research technologies and methods, is manifestly inconsistent with the design perspective on the cell, thus creating an apparent para...

    Authors: Alexei Kurakin
    Citation: Theoretical Biology and Medical Modelling 2010 7:12
  15. It is reasonable to consider the thalamus a primary candidate for the location of consciousness, given that the thalamus has been referred to as the gateway of nearly all sensory inputs to the corresponding co...

    Authors: Byoung-Kyong Min
    Citation: Theoretical Biology and Medical Modelling 2010 7:10
  16. The Minimal Model, (MM), used to assess insulin sensitivity (IS) from Intra-Venous Glucose-Tolerance Test (IVGTT) data, suffers from frequent lack of identifiability (parameter estimates with Coefficients of V...

    Authors: Simona Panunzi, Andrea De Gaetano and Geltrude Mingrone
    Citation: Theoretical Biology and Medical Modelling 2010 7:9
  17. A tendency to develop reentry orthostasis after a prolonged exposure to microgravity is a common problem among astronauts. The problem is 5 times more prevalent in female astronauts as compared to their male c...

    Authors: Richard L Summers, Steven Platts, Jerry G Myers and Thomas G Coleman
    Citation: Theoretical Biology and Medical Modelling 2010 7:8
  18. Signal transduction networks represent the information processing systems that dictate which dynamical regimes of biochemical activity can be accessible to a cell under certain circumstances. One of the major ...

    Authors: Jayson Gutiérrez, Georges St Laurent III and Silvio Urcuqui-Inchima
    Citation: Theoretical Biology and Medical Modelling 2010 7:7
  19. The order retroviridae comprises viruses based on ribonucleic acids (RNA). Some, such as HIV and HTLV, are human pathogens. Newly emerged human retroviruses have zoonotic origins. As far as has been establishe...

    Authors: Misaki Wayengera
    Citation: Theoretical Biology and Medical Modelling 2010 7:5
  20. The robust storage, updating and utilization of information are necessary for the maintenance and perpetuation of dynamic systems. These systems can exist as constructs of metal-oxide semiconductors and silico...

    Authors: David J D'Onofrio and Gary An
    Citation: Theoretical Biology and Medical Modelling 2010 7:3
  21. In many parts of the world, the exponential growth rate of infections during the initial epidemic phase has been used to make statistical inferences on the reproduction number, R, a summary measure of the transmi...

    Authors: Hiroshi Nishiura, Gerardo Chowell, Muntaser Safan and Carlos Castillo-Chavez
    Citation: Theoretical Biology and Medical Modelling 2010 7:1
  22. After our work was published, we found that some of the terms in the equations were incorrect and that there were some typographical errors in the abbreviations.

    Authors: Hirotaka Ando, Shigeru Izawa, Wataru Hori and Ippei Nakagawa
    Citation: Theoretical Biology and Medical Modelling 2009 6:29

    The original article was published in Theoretical Biology and Medical Modelling 2008 5:19

  23. In silico techniques are highly suited for both the discovery of new and development of existing vaccines. Enterohemorrhagic Escherichia coli O157:H7 (EHEC) exhibits a pattern of localized adherence to host cells...

    Authors: Jafar Amani, S Latif Mousavi, Sima Rafati and Ali H Salmanian
    Citation: Theoretical Biology and Medical Modelling 2009 6:28
  24. Mere possibility is not an adequate basis for asserting scientific plausibility. A precisely defined universal bound is needed beyond which the assertion of plausibility, particularly in life-origin models, can b...

    Authors: David L Abel
    Citation: Theoretical Biology and Medical Modelling 2009 6:27
  25. The physiological fact that a stable level of brain glucose is more important than that of blood glucose suggests that the ultimate goal of the glucose-insulin-glucagon (GIG) regulatory system may be homeostas...

    Authors: Lu Gaohua and Hidenori Kimura
    Citation: Theoretical Biology and Medical Modelling 2009 6:26
  26. Phytophthora infestans is a devastating oomycete pathogen of potato production worldwide. This review explores the use of computational models for studying the molecular interactions between P. infestans and one ...

    Authors: Andrés Pinzón, Emiliano Barreto, Adriana Bernal, Luke Achenie, Andres F González Barrios, Raúl Isea and Silvia Restrepo
    Citation: Theoretical Biology and Medical Modelling 2009 6:24
  27. The formal kinetics of the H1N1 epidemic seems to take the form of an exponential curve. There is a good correlation between this theoretical model and epidemiological data on the number of H1N1-infected peopl...

    Authors: Konstantin G Gurevich
    Citation: Theoretical Biology and Medical Modelling 2009 6:23
  28. The filamentous fungus Moniliophthora perniciosa (Stahel) Aime & Phillips-Mora is a hemibiotrophic Basidiomycota that causes witches' broom disease of cocoa (Theobroma cacao L.). This disease has resulted in a se...

    Authors: Bruno S Andrade, Alex G Taranto, Aristóteles Góes-Neto and Angelo A Duarte
    Citation: Theoretical Biology and Medical Modelling 2009 6:22
  29. The scheme of the core vestibular membranes, consisting of serially connected utricle, ampulla and semicircular canal, first appeared hundreds of millions of years ago in primitive fish and has remained largel...

    Authors: Daniel J Pender
    Citation: Theoretical Biology and Medical Modelling 2009 6:19
  30. Polycystic ovary syndrome (PCOS) is a complex but frequently occurring endocrine abnormality. PCOS has become one of the leading causes of oligo-ovulatory infertility among premenopausal women. The definition ...

    Authors: Zeti-Azura Mohamed-Hussein and Sarahani Harun
    Citation: Theoretical Biology and Medical Modelling 2009 6:18
  31. Cardiac tamponade is a condition whereby fluid accumulation in the pericardial sac surrounding the heart causes elevation and equilibration of pericardial and cardiac chamber pressures, reduced cardiac output,...

    Authors: Deepa Ramachandran, Chuan Luo, Tony S Ma and John W Clark Jr
    Citation: Theoretical Biology and Medical Modelling 2009 6:15
  32. Mosquitoes are the transmissive vectors for several infectious pathogens that affect man. However, the control of mosquitoes through insecticide and pesticide spraying has proved difficult in the past. We hypo...

    Authors: Wilson Byarugaba, Henry Kajumbula and Misaki Wayengera
    Citation: Theoretical Biology and Medical Modelling 2009 6:14