Theoretical Biology and Medical Modelling

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Research

Possible contribution of quantum-like correlations to the placebo effect: consequences on blind trials

Francis Beauvais

Published on: 2 June 2017
Research

Markov modeling in hepatitis B screening and linkage to care

Martin A. Sehr, Kartik D. Joshi, John M. Fontanesi, Robert J. Wong, Robert R. Bitmead and Robert G. Gish

Published on: 18 May 2017
Research

Image-driven modeling of the proliferation and necrosis of glioblastoma multiforme

Vishal Patel and Leith Hathout

Published on: 2 May 2017
Research

A highly pathogenic simian/human immunodeficiency virus effectively produces infectious virions compared with a less pathogenic virus in cell culture

Shoya Iwanami, Yusuke Kakizoe, Satoru Morita, Tomoyuki Miura, Shinji Nakaoka and Shingo Iwami

Published on: 21 April 2017
Research

Establishment of a new initial dose plan for vancomycin using the generalized linear mixed model

Yasuyuki Kourogi, Kenji Ogata, Norito Takamura, Jin Tokunaga, Nao Setoguchi, Mitsuhiro Kai, Emi Tanaka and Susumu Chiyotanda

Published on: 8 April 2017

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Research

Structural, phylogenetic and docking studies of D-amino acid oxidase activator (DAOA), a candidate schizophrenia gene

Sheikh Arslan Sehgal, Naureen Aslam Khattak and Asif Mir

Published on: 4 January 2013
Commentary

Dynamic models of immune responses: what is the ideal level of detail?

Juilee Thakar, Mary Poss, Réka Albert, Gráinne H Long and Ranran Zhang

Published on: 20 August 2010
Research

Serotonin synthesis, release and reuptake in terminals: a mathematical model

Janet Best, H Frederik Nijhout and Michael Reed

Published on: 19 August 2010
Research

The homeostatic set point of the hypothalamus-pituitary-thyroid axis – maximum curvature theory for personalized euthyroid targets

Melvin Khee-Shing Leow and Simon L Goede

Published on: 8 August 2014
Research

The biochemistry of acetaminophen hepatotoxicity and rescue: a mathematical model

Rotem Ben-Shachar, Yifei Chen, Shishi Luo, Catherine Hartman, Michael Reed and H Frederik Nijhout

Published on: 19 December 2012

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Aims and scope

Theoretical Biology and Medical Modelling is an open access peer-reviewed journal adopting a broad definition of "biology" and focusing on theoretical ideas and models associated with developments in biology and medicine. Mathematicians, biologists and clinicians of various specialisms, philosophers and historians of science are all contributing to the emergence of novel concepts in an age of systems biology, bioinformatics and computer modelling. This is the field in which Theoretical Biology and Medical Modelling operates. We welcome submissions that are technically sound and offering either improved understanding in biology and medicine or progress in theory or method.

Featured article: Assessing potential countermeasures against the dengue epidemic in non-tropical urban cities

Masui et al. model the spread of dengue in an urban environment, and find that reducing movement between high-risk and low risk areas, as in quarantine, may actually promote the spread of the disease, contrary to expectations.

The authors of this article have also written an entry on the BioMed Central blog, On Biology:

Dengue and quarantine – not as simple as you think

Editor-in-Chief

Professor Hiroshi Nishiura

Professor Nishiura is an Associate Professor at the Graduate School of Medicine, The University of Tokyo. He is cosmopolitan-minded, having worked for 10 years for different infectious disease modeling groups at Imperial College London, University of Tuebingen (Germany), University of Utrecht (The Netherlands) and the University of Hong Kong, before returning back to Japan in 2013. His research interests span the areas of statistical epidemiology of infectious diseases, epidemiological modeling and biomathematical formulation of the transmission dynamics of infectious diseases. He aims to answer policy-relevant questions by integrating various mathematical models with empirically observed data. A common thread in his research is an understanding of the epidemiological dynamics underlying empirically observed data.