Figure 1From: Cosinor-based rhythmometryDefinition of rhythm characteristics. The MESOR is a rhythm-adjusted mean; the double amplitude (2A) is a measure of the extent of predictable change within a cycle; the acrophase is a measure of the timing of overall high values recurring in each cycle, expressed in (negative) degrees in relation to a reference time set to 0°, with 360° equated to the period; and the period is the duration of one cycle. © Halberg Chronobiology Center.Back to article page