Table 2 The common pathways associated to down-regulated genes.
From: Pathway landscapes and epigenetic regulation in breast cancer and melanoma cell lines
Type CCL | Pathway name | Genes | p-value | q-value |
|---|---|---|---|---|
Melanoma | Cytokine-cytokine receptor interaction* | CSF2RB; IL2RA; TNFSF18; TNFSF15; IFNA1; IL13; IL4; IL12A; IFNB1; TNFRSF10B; BMPR1B; IFNA8; IFNA5; TNFRSF18; LIFR | 3.63E-11 | 4.24E-09 |
BC | Â | IL2RA; IFNA8; IFNA1; BMPR1B; TNFSF8; IL2; IL26; TNFRSF18 | 2.92E-04 | 1.61E-02 |
Melanoma | Jak-stat signaling pathway* | CSF2RB; IL2RA; IFNA8; IFNA1; IL13; IFNA5; IFNB1; IL4; IL12A; LIFR | 3.09E-08 | 1.81E-06 |
BC | Â | IL2RA; IFNA1; IFNA8; IL2; IL26 | 3.41E-03 | 6.86E-02 |
Melanoma | PI3K-AKT signaling pathway# | IL2RA; IFNA8; IFNA1; IFNA5; IFNB1; IL4; FGF12; MDM2; FGF20 | 2.11E-04 | 1.76E-03 |
BC | Â | IL2RA; IFNA8; IFNA1; THBS2; RXRA; IL2; FGF12; TSC2; FGF20 | 3.39E-04 | 1.61E-02 |
Melanoma | Nuclear receptor transcription pathway# | NR1D1; AR; NR2E1 | 3.84E-03 | 1.36E-02 |
BC | Â | NR1D1; NR2E1; RXRA; RORB | 3.43E-04 | 1.61E-02 |
Melanoma | Autoimmune thyroid disease | IL4; IFNA8; IFNA1; IFNA5 | 2.71E-04 | 1.98E-03 |
BC | Â | IFNA1; IFNA8; IL2 | 4.56E-03 | 7.15E-02 |