Nucleic acid chaperons: a theory of an RNA-assisted protein folding

Table I Amino Acids Coded by Partially Complementary Codons

D_1X3/RC_3X1			1st	G	T	G	G	T	G	C	A	A	CT	A	A	C	C	AC	AT	A	G	T	T
			2nd	C	G	A	A	T	G	A	T	A	T	T	A	C	A	G	CG	C	T	G	A
			3rd	X	CT	CT	AG	CT	X	CT	ACT	AG	XAG	G	CT	X	AG	AGX	CTX	X	X	G	CT
1st	2nd	3rd	AA	A	C	D	E	F	G	H	I	K	L	M	N	P	Q	R	S	T	V	W	Y
G	C	X	A	+	+	+		+	+	+	+		+		+	+		+	+	+	+		+
T	G	CT	C	+			+		+		+	+						+		+	+
G	A	CT	D	+		+			+		+				+				+	+	+
G	A	AG	E		+			+		+			+			+		+	+				+
T	T	CT	F	+			+		+		+	+						+		+	+
G	G	X	G	+	+	+		+	+	+	+		+		+	+		+	+	+	+		+
C	A	CT	H	+			+		+			+		+				+		+	+
A	T	ACT	I	+	+	+		+	+		+				+				+	+	+		+
A	A	AG	K		+			+		+			+			+		+	+				+
CT	T	XAG	L	+			+		+			+	+	+		+	+	+	+	+	+	+
A	T	G	M							+			+			+		+
A	A	CT	N	+		+			+		+				+				+	+	+
C	C	X	P	+			+		+			+	+	+		+	+	+	+	+	+	+
C	A	AG	Q										+			+	+	+	+			+
AC	G	AGX	R	+	+		+	+	+	+		+	+	+		+	+	+	+	+	+	+	+
AT	CG	CTX	S	+		+	+		+		+	+	+		+	+	+	+	+	+	+
A	C	X	T	+	+	+		+	+	+	+		+		+	+		+	+	+	+		+
G	T	X	V	+	+	+		+	+	+	+		+		+	+		+	+	+	+		+
T	G	G	W										+			+	+	+
T	A	CT	Y	+			+		+		+	+						+		+	+

RC_3X1 code: 1st and 3rd codon letters are complementary in reverse order, indicated by complementary colors (red, blue); X: any residue; AA: amino acids, one-letter code, +: AAs coded by the D_1x3/RC_3X1 complementary codons

ISSN: 1742-4682

D_1X3/RC_3X1			1st	G	T	G	G	T	G	C	A	A	CT	A	A	C	C	AC	AT	A	G	T	T
			2nd	C	G	A	A	T	G	A	T	A	T	T	A	C	A	G	CG	C	T	G	A
			3rd	X	CT	CT	AG	CT	X	CT	ACT	AG	XAG	G	CT	X	AG	AGX	CTX	X	X	G	CT
1st	2nd	3rd	AA	A	C	D	E	F	G	H	I	K	L	M	N	P	Q	R	S	T	V	W	Y
G	C	X	A	+	+	+		+	+	+	+		+		+	+		+	+	+	+		+
T	G	CT	C	+			+		+		+	+						+		+	+
G	A	CT	D	+		+			+		+				+				+	+	+
G	A	AG	E		+			+		+			+			+		+	+				+
T	T	CT	F	+			+		+		+	+						+		+	+
G	G	X	G	+	+	+		+	+	+	+		+		+	+		+	+	+	+		+
C	A	CT	H	+			+		+			+		+				+		+	+
A	T	ACT	I	+	+	+		+	+		+				+				+	+	+		+
A	A	AG	K		+			+		+			+			+		+	+				+
CT	T	XAG	L	+			+		+			+	+	+		+	+	+	+	+	+	+
A	T	G	M							+			+			+		+
A	A	CT	N	+		+			+		+				+				+	+	+
C	C	X	P	+			+		+			+	+	+		+	+	+	+	+	+	+
C	A	AG	Q										+			+	+	+	+			+
AC	G	AGX	R	+	+		+	+	+	+		+	+	+		+	+	+	+	+	+	+	+
AT	CG	CTX	S	+		+	+		+		+	+	+		+	+	+	+	+	+	+
A	C	X	T	+	+	+		+	+	+	+		+		+	+		+	+	+	+		+
G	T	X	V	+	+	+		+	+	+	+		+		+	+		+	+	+	+		+
T	G	G	W										+			+	+	+
T	A	CT	Y	+			+		+		+	+						+		+	+

D_1X3/RC_3X1			1st	G	T	G	G	T	G	C	A	A	CT	A	A	C	C	AC	AT	A	G	T	T
			2nd	C	G	A	A	T	G	A	T	A	T	T	A	C	A	G	CG	C	T	G	A
			3rd	X	CT	CT	AG	CT	X	CT	ACT	AG	XAG	G	CT	X	AG	AGX	CTX	X	X	G	CT
1st	2nd	3rd	AA	A	C	D	E	F	G	H	I	K	L	M	N	P	Q	R	S	T	V	W	Y
G	C	X	A	+	+	+		+	+	+	+		+		+	+		+	+	+	+		+
T	G	CT	C	+			+		+		+	+						+		+	+
G	A	CT	D	+		+			+		+				+				+	+	+
G	A	AG	E		+			+		+			+			+		+	+				+
T	T	CT	F	+			+		+		+	+						+		+	+
G	G	X	G	+	+	+		+	+	+	+		+		+	+		+	+	+	+		+
C	A	CT	H	+			+		+			+		+				+		+	+
A	T	ACT	I	+	+	+		+	+		+				+				+	+	+		+
A	A	AG	K		+			+		+			+			+		+	+				+
CT	T	XAG	L	+			+		+			+	+	+		+	+	+	+	+	+	+
A	T	G	M							+			+			+		+
A	A	CT	N	+		+			+		+				+				+	+	+
C	C	X	P	+			+		+			+	+	+		+	+	+	+	+	+	+
C	A	AG	Q										+			+	+	+	+			+
AC	G	AGX	R	+	+		+	+	+	+		+	+	+		+	+	+	+	+	+	+	+
AT	CG	CTX	S	+		+	+		+		+	+	+		+	+	+	+	+	+	+
A	C	X	T	+	+	+		+	+	+	+		+		+	+		+	+	+	+		+
G	T	X	V	+	+	+		+	+	+	+		+		+	+		+	+	+	+		+
T	G	G	W										+			+	+	+
T	A	CT	Y	+			+		+		+	+						+		+	+

D_1X3/RC_3X1			1st	G	T	G	G	T	G	C	A	A	CT	A	A	C	C	AC	AT	A	G	T	T
			2nd	C	G	A	A	T	G	A	T	A	T	T	A	C	A	G	CG	C	T	G	A
			3rd	X	CT	CT	AG	CT	X	CT	ACT	AG	XAG	G	CT	X	AG	AGX	CTX	X	X	G	CT
1st	2nd	3rd	AA	A	C	D	E	F	G	H	I	K	L	M	N	P	Q	R	S	T	V	W	Y
G	C	X	A	+	+	+		+	+	+	+		+		+	+		+	+	+	+		+
T	G	CT	C	+			+		+		+	+						+		+	+
G	A	CT	D	+		+			+		+				+				+	+	+
G	A	AG	E		+			+		+			+			+		+	+				+
T	T	CT	F	+			+		+		+	+						+		+	+
G	G	X	G	+	+	+		+	+	+	+		+		+	+		+	+	+	+		+
C	A	CT	H	+			+		+			+		+				+		+	+
A	T	ACT	I	+	+	+		+	+		+				+				+	+	+		+
A	A	AG	K		+			+		+			+			+		+	+				+
CT	T	XAG	L	+			+		+			+	+	+		+	+	+	+	+	+	+
A	T	G	M							+			+			+		+
A	A	CT	N	+		+			+		+				+				+	+	+
C	C	X	P	+			+		+			+	+	+		+	+	+	+	+	+	+
C	A	AG	Q										+			+	+	+	+			+
AC	G	AGX	R	+	+		+	+	+	+		+	+	+		+	+	+	+	+	+	+	+
AT	CG	CTX	S	+		+	+		+		+	+	+		+	+	+	+	+	+	+
A	C	X	T	+	+	+		+	+	+	+		+		+	+		+	+	+	+		+
G	T	X	V	+	+	+		+	+	+	+		+		+	+		+	+	+	+		+
T	G	G	W										+			+	+	+
T	A	CT	Y	+			+		+		+	+						+		+	+