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Table 3 Comparison of the experimental fluxes to that computed from E. coli model. The reaction step SYN was not explicitly mentioned by Zhao et al. [15], but was shown by a branch from αKG.

From: Kinetic modeling of tricarboxylic acid cycle and glyoxylate bypass in Mycobacterium tuberculosis, and its application to assessment of drug targets

Reaction step

Growth on glucose (Experimental)

Growth on glucose (Simulation)

Growth on acetate (Experimental)

Growth on acetate (Simulation)

CS

50

50

73.4

73.4

ACN

50

50

73.4

73.4

ICD

50

49.9

52.8

56.1

KDH

40.6

40.5

51.0

54.2

ScAS

40.6

40.5

51.0

54.2

SDH

40.6

40.6

71.6

71.5

FUM

40.6

40.6

71.6

71.5

MDH

40.6

40.7

86.3

88.7

SYN

9.4

9.4

1.8

1.9

ICL

0

0.1

20.6

17.2

MS

0

0.1

20.6

17.2