Figure 6From: A mathematical model separates quantitatively the cytostatic and cytotoxic effects of a HER2 tyrosine kinase inhibitorA The age-dependent probability of division φ (solid blue line) and the corresponding division rate β (dashed green line) are shown. φ is given by a shifted Γ-distribution with mean 19 h (equation (10)). Observe that the units of a are hours. However, cytostatic effects result in a slowed progression through the cell cycle. B We show the cell-phase-dependent tendency of cells to become nonproliferating μ(a) (see equation (7)).Back to article page