Figure 8

Dysregulation of Axiom 6 and its effect on ISEA CULTURE growth. Axiom 6 dictates oriented placement of a newly created CELL. It is placed at an adjacent MATRIX position that maximizes its number of CELL neighbors. CELLS followed Axiom 6 with a parameter-controlled probability, p. Otherwise, the CELL copy replaced a randomly selected MATRIX neighbor without regard for CELL neighbor number. Doing so changed ISEA growth and structural characteristics. (A-B) CELL count increased monotonically with the severity of dysregulation. Compared to ISEA1 growth (A), ISEA2 growth was affected less for every dysregulation level. (C) CELL count after 50 simulation cycles showed marked differences between ISEA1 and ISEA2 that increased with the severity of dysregulation.