Table 1 Calibrated values for the parameters in the model
From: The effects of time valuation in cancer optimal therapies: a study of chronic myeloid leukemia
Parameter | Description | Value | Units |
|---|---|---|---|
n | Normal HSC division rate | 0.00357 | /day |
m | Cancer HSC division rate | 0.0037 | /day |
d 0 | Normal HSC mortality rate | 0.005 | /day |
g 0 | Cancer HSC mortality rate | 0.0003 | /day |
r | Normal DC production rate | 1011.5 | /day |
q | Cancer DC production rate | 1011.5 | /day |
d | Normal DC mortality rate | 1.25 | /day |
d 2 | Normal DC proliferation rate | 0.25 | /day |
g | Cancer DC mortality rate | 1.1 | /day |
g 2 | Cancer DC proliferation rate | 0.5 | /day |
K | Carrying Capacity of Bone Marrow | 12791 | HSC/day |