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Table 2 Similarities among Bunyavirus Gc, Alphavirus E1 and related glycoproteins as determined with the PRSS3 sequence algorithm.

From: Proteomics computational analyses suggest that the carboxyl terminal glycoproteins of Bunyaviruses are class II viral fusion protein (beta-penetrenes)

  Viral protein 1
Viral protein Hanta HAN Gc Nairo CCHF Gc Phlebo RVF Gc Tospo TSWV Gc Alpha SIN E1 CeRV Cer13 Env2 Tenui RiSV pvc22 Flavi TBEV E
Obuny BUN Gc 0.0005 0.01 0.009 10-5 NS NS NS NS
Hanta HAN Gc --- 0.0001 NS NS 0.05 NS 0.003 NS
Nairo CCHF Gc --- --- 0.05 0.0001 NS NS NS NS
Phlebo RVF Gc --- --- --- 10-18 0.04 10-8 0.001 NS
Tospo TSWV Gc --- --- --- --- NS NS NS NS
Alpha SIN E1 --- --- --- --- --- 0.02 NS NS
CeRV Cer13 Env2 --- --- --- --- --- --- 0.02 NS
Tenui RiSV pvc22 --- --- --- --- --- --- --- NS
  1. Two-way comparisons were done between the full-length amino acid sequences of the indicated glycoproteins. Probabilities (p values) of a significant alignment are based on 1000 shuffles. BUN: Bunyamwera virus; HAN: Hantavirus; CCFV: Crimean-Congo hemorrhagic fever virus; RVF: Rift valley fever virus; TSWV: Tomato spotted wilt virus; SIN: Sindbis virus; Cer13: Caenorhabditis elegans retrovirus 13; RiSV; rice stripe virus; TBEV: tick-borne encephalitis virus.
  2. 2C-terminal sequence.