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Table 2 Similarities among Bunyavirus Gc, Alphavirus E1 and related glycoproteins as determined with the PRSS3 sequence algorithm.

From: Proteomics computational analyses suggest that the carboxyl terminal glycoproteins of Bunyaviruses are class II viral fusion protein (beta-penetrenes)

 

Viral protein 1

Viral protein

Hanta HAN Gc

Nairo CCHF Gc

Phlebo RVF Gc

Tospo TSWV Gc

Alpha SIN E1

CeRV Cer13 Env2

Tenui RiSV pvc22

Flavi TBEV E

Obuny BUN Gc

0.0005

0.01

0.009

10-5

NS

NS

NS

NS

Hanta HAN Gc

---

0.0001

NS

NS

0.05

NS

0.003

NS

Nairo CCHF Gc

---

---

0.05

0.0001

NS

NS

NS

NS

Phlebo RVF Gc

---

---

---

10-18

0.04

10-8

0.001

NS

Tospo TSWV Gc

---

---

---

---

NS

NS

NS

NS

Alpha SIN E1

---

---

---

---

---

0.02

NS

NS

CeRV Cer13 Env2

---

---

---

---

---

---

0.02

NS

Tenui RiSV pvc22

---

---

---

---

---

---

---

NS

  1. Two-way comparisons were done between the full-length amino acid sequences of the indicated glycoproteins. Probabilities (p values) of a significant alignment are based on 1000 shuffles. BUN: Bunyamwera virus; HAN: Hantavirus; CCFV: Crimean-Congo hemorrhagic fever virus; RVF: Rift valley fever virus; TSWV: Tomato spotted wilt virus; SIN: Sindbis virus; Cer13: Caenorhabditis elegans retrovirus 13; RiSV; rice stripe virus; TBEV: tick-borne encephalitis virus.
  2. 2C-terminal sequence.