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Table 3 Similarities among Bunyavirus Gn, Alphavirus E2 and related glycoproteins as determined with the PRSS3 sequence algorithm.

From: Proteomics computational analyses suggest that the carboxyl terminal glycoproteins of Bunyaviruses are class II viral fusion protein (beta-penetrenes)

 

Viral protein 1

Viral protein

Hanta HAN Gn

Nairo CCHF Gn

Phlebo RVF Gn

Tospo TSWV Gn

Alpha SIN E2

CeRV Cer13 Env2

Tenui RiSV pvc22

Flavi TBEV E

Obuny BUN Gn

NS

NS

NS

0.02

NS

NS

NS

NS

Hanta HAN Gn

---

10-4

0.03

NS

0.05

NS

NS

NS

Nairo CCHF Gn

---

---

NS

NS

NS

NS

NS

NS

Phlebo RVF Gn

---

---

---

NS

NS

NS

NS3

NS

Tospo TSWV Gn

---

---

---

---

0.04

NS

NS

NS

Alpha SIN E2

---

---

---

---

---

NS

0.04

NS

CeRV Cer13 Env2

---

---

---

---

---

---

0.025

NS

Tenui RiSV pvc22

---

---

---

---

---

---

---

NS

  1. 1Two-way comparisons were done between the full-length amino acid sequences of the indicated glycoproteins. Probabilities (p values) of a significant alignment are based on 1000 shuffles. BUN: Bunyamwera virus; HAN: Hantavirus; CCFV: Crimean-Congo hemorrhagic fever virus; RVF: Rift valley fever virus; TSWV: Tomato spotted wilt virus; SIN: Sindbis virus; Cer13: Caenorhabditis elegans retrovirus 13; RiSV; rice stripe virus; TBEV: tick-borne encephalitis virus.
  2. 2N-terminal sequence.
  3. 3p = 0.08