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Table 3 Similarities among Bunyavirus Gn, Alphavirus E2 and related glycoproteins as determined with the PRSS3 sequence algorithm.

From: Proteomics computational analyses suggest that the carboxyl terminal glycoproteins of Bunyaviruses are class II viral fusion protein (beta-penetrenes)

  Viral protein 1
Viral protein Hanta HAN Gn Nairo CCHF Gn Phlebo RVF Gn Tospo TSWV Gn Alpha SIN E2 CeRV Cer13 Env2 Tenui RiSV pvc22 Flavi TBEV E
Obuny BUN Gn NS NS NS 0.02 NS NS NS NS
Hanta HAN Gn --- 10-4 0.03 NS 0.05 NS NS NS
Nairo CCHF Gn --- --- NS NS NS NS NS NS
Phlebo RVF Gn --- --- --- NS NS NS NS3 NS
Tospo TSWV Gn --- --- --- --- 0.04 NS NS NS
Alpha SIN E2 --- --- --- --- --- NS 0.04 NS
CeRV Cer13 Env2 --- --- --- --- --- --- 0.025 NS
Tenui RiSV pvc22 --- --- --- --- --- --- --- NS
  1. 1Two-way comparisons were done between the full-length amino acid sequences of the indicated glycoproteins. Probabilities (p values) of a significant alignment are based on 1000 shuffles. BUN: Bunyamwera virus; HAN: Hantavirus; CCFV: Crimean-Congo hemorrhagic fever virus; RVF: Rift valley fever virus; TSWV: Tomato spotted wilt virus; SIN: Sindbis virus; Cer13: Caenorhabditis elegans retrovirus 13; RiSV; rice stripe virus; TBEV: tick-borne encephalitis virus.
  2. 2N-terminal sequence.
  3. 3p = 0.08