Table 1 Results of direct curve fitting of the exponential and the Gompertzian growth models to tumour volume data from two patients
From: A new method to estimate parameters of the growth model for metastatic tumours
Patient (year of birth) | Tumour type | Tumour (V cm3) | Number of data points | Growth model | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
Exponential | Gompertzian | |||||||||
SGR0(%/day) | Year of formation | r2 | SGR0(%/day) | λ (1/d) | Year of formation | r2 | ||||
1 (1952) | Liver metastases from a primary midgut carcinoid | A (614) | 8 | 0.14 | 1947 | 0.972 | 1.1 | 0.0004 | 1983 | 0.988 |
B (171) | 8 | 0.15 | 1956 | 0.992 | 0.2 | 0 | 1956 | 0.989 | ||
C (8) | 3 | 0.22 | 1971 | 1.000 | 0.3 | 0 | 1976 | 0.954 | ||
D (9) | 4 | 0.27 | 1978 | 0.997 | 1.3 | 0.0005 | 1991 | 1.000 | ||
E (4) | 2 | 0.33 | 1982 | 1.000 | - | - | - | - | ||
F (3) | 2 | 0.31 | 1982 | 1.000 | - | - | - | - | ||
2 (1941) | Lung metastases from a primary renal cell carcinoma | A (82) | 3 | 0.32 | 1973 | 0.998 | 3.8 | 0.0014 | 1992 | 1.000 |
B (635) | 19 | 0.24 | 1968 | 0.992 | 0.5 | 0.0001 | 1977 | 0.993 | ||
C (489) | 12 | 0.33 | 1976 | 0.939 | 0.4 | 0 | 1977 | 0.938 | ||
D (54) | 7 | 0.38 | 1980 | 0.986 | 1.8 | 0.0006 | 1991 | 0.990 | ||
E (8) | 6 | 0.14 | 1953 | 0.798 | 0.1 | 0 | 1953 | 0.791 | ||
F (11) | 5 | 0.22 | 1970 | 0.946 | 0.4 | 0.0001 | 1978 | 0.944 | ||
G (7) | 4 | 0.39 | 1983 | 0.998 | 0.5 | 0 | 1987 | 0.970 | ||