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Figure 1 | Theoretical Biology and Medical Modelling

Figure 1

From: A physiologically-based flow network model for hepatic drug elimination II: variable lattice lobule models

Figure 1

(a) Schematic diagram of a cross section of hepatic parenchyma consisting of hexagonal lobules, and the portal and hepatic veins. The lobule contains liver cells called hepatocytes and blood vessels called sinusoids. The segment represents a typical area studied in this paper. (b) Homogeneous lattice (segmented area). The high porosity bands represent sinusoids and the lower porosity regions represent tissue containing hepatocytes. The Base case lattice as shown here has tissue porosity 0.2382. The ideal case lattice (not shown) has tissue porosity 0.4764. The extracellular matrix (ECM) case lattice (not shown) has tissue porosity 0.1191.

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