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Figure 3 | Theoretical Biology and Medical Modelling

Figure 3

From: Dynamic simulation of red blood cell metabolism and its application to the analysis of a pathological condition

Figure 3

Computer simulation time-course of metabolic intermediates. Changes in the concentrations of ATP (A), GO6P (B), GSH (C), GSSG (D), NADP (E) and NADPH (F) during the RBC simulation. The simulation was run for 200,000 seconds (Approx. 55 h) in simulation time. Concentrations change when G6PD kinetic parameters are shifted from the normal to pathological values (Table 3). ATP became depleted at around 20 h.

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Theoretical Biology and Medical Modelling

ISSN: 1742-4682