Figure 1

In vivo response for monophasic dose-effect curves measured in vitro. B = 1. a) equation (6), b) equation (7). k _el = 0.0714 1/min, k ₁ = 0.0277 1/min, C ₀ = 1 nM, γ = β. Illustrative values for fig. 1, 2, 4 taken from Veldhuis et al., (1993) [8] and similar to those measured by Baumann et al., (1987)⁹ for the clearance of growth hormone (GH).