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Figure 8 | Theoretical Biology and Medical Modelling

Figure 8

From: A discrete Single Delay Model for the Intra-Venous Glucose Tolerance Test

Figure 8

Comparison between different methods of data fitting. Each figure reports Glucose (white circles) and Insulin (black diamonds) observed concentrations versus time, together with the predicted time-curves (dashed line for Glucose and continuous line for Insulin) using four different methods: the discrete Single Delay Model (figure 8.a); the Minimal Model with its traditional two-pass 'decoupling' estimation method (figure 8.b); the Minimal Model when all parameters are fitted simultaneously (figure 8.c); the Minimal Model when global system behavior (interacting glycemias and insulinemias) is reconstructed from separately estimated (two-pass) parameters (figure 8.d).

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