Cerebral hypoxia. Effect of oxygen deprivation of brain cells on metabolic fluxes calculated by MOMA approach. All the x-axes represent the oxygen flux, CMRO2, available to brain cells. It is changed from anoxic level (no oxygen uptake) to the basal level (1.760 μmole/g/min). The title of each sub-figure includes the reaction number of the plotted flux, as given in Additional File 1.