Table 1 Parameter values that were used in the simulations of the basic model.
Parameter | Description | Value (units) | |
|---|---|---|---|
λ | Production rate of uninfected cells | 10.0 | (cells/day) |
d | Rate of uninfected cell die-off | 0.1 | (day-1) |
β | Rate infected cells are produced from uninfected cells and free virus | 0.01 | (virion·day-1) |
a | Infected cell death rate (due to virus) | 0.5 | (day-1) |
p | Rate that infected cells are killed by CTL E cells | 1.0 | (cells/day) |
b | Rate that CTL P die-off | 0.001 | (day-1) |
q | Fraction of CTL P cells that proliferate into CTL E cells | 0.1 | (T-cell/T-cell) |
h | Rate of CTL E die-off | 0.1 | (day-1) |
k | Rate at which free virions are produced from infected cells | 3.0 | (virion·day-1) |
u | Viral decay rate | 3.0 | (day-1) |