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Table 1 The MLEs of parameters that define circadian rhythms for three different QTL genotypes, the structure of the covariance matrix and the association between the marker and QTL in a natural population, taking the heritability of the assumed QTL as H2 = 0.1. The numbers in parentheses are the square roots of the mean square errors of the MLEs.

From: A computational model for functional mapping of genes that regulate intra-cellular circadian rhythms

Rhythmic Parameters
  AA Aa aa
  Given MLE Given MLE Given MLE
n 1.50 1.57(0.067) 1.40 1.54(0.139) 1.70 1.74(0.045)
m 3.00 3.02(0.018) 2.90 2.91(0.010) 2.80 2.79(0.050)
r M 1.10 1.16(0.060) 1.30 1.35(0.054) 0.90 0.98(0.083)
r P 0.30 0.30(0.020) 0.35 0.36(0.007) 0.40 0.39(0.001)
q M 0.16 0.15(0.008) 0.17 0.16(0.011) 0.18 0.17(0.012)
q P 0.16 0.16(0.001) 0.17 0.16(0.005) 0.18 0.18(0.001)
Matrix Structuring Parameters
  Given MLE     
φ x 0.010 0.011(0.001)     
φ y -0.100 0.098(0.001)     
ψ x 0.100 0.105(0.005)     
ψ y -0.200 -0.206(0.006)     
δ x 2 MathType@MTEF@5@5@+=feaafiart1ev1aaatCvAUfKttLearuWrP9MDH5MBPbIqV92AaeXatLxBI9gBaebbnrfifHhDYfgasaacH8akY=wiFfYdH8Gipec8Eeeu0xXdbba9frFj0=OqFfea0dXdd9vqai=hGuQ8kuc9pgc9s8qqaq=dirpe0xb9q8qiLsFr0=vr0=vr0dc8meaabaqaciaacaGaaeqabaqabeGadaaakeaaiiGacqWF0oazdaqhaaWcbaGaemiEaGhabaGaeGOmaidaaaaa@30F0@ 0.223 0.223(0.001)     
δ y 2 MathType@MTEF@5@5@+=feaafiart1ev1aaatCvAUfKttLearuWrP9MDH5MBPbIqV92AaeXatLxBI9gBaebbnrfifHhDYfgasaacH8akY=wiFfYdH8Gipec8Eeeu0xXdbba9frFj0=OqFfea0dXdd9vqai=hGuQ8kuc9pgc9s8qqaq=dirpe0xb9q8qiLsFr0=vr0=vr0dc8meaabaqaciaacaGaaeqabaqabeGadaaakeaaiiGacqWF0oazdaqhaaWcbaGaemyEaKhabaGaeGOmaidaaaaa@30F2@ 1.842 1.742(0.100)     
ρ 0.200 0.216(0.016)     
Genetic Parameters
  Given MLE     
p 0.6 0.601(0.003)     
q 0.6 0.501(0.094)     
D 0.08 0.068(0.012)