Overlap in terminology of nucleic acid folding Donald Forsdyke, Queen's University, Canada 20 September 2008 There is a profusion of overlapping terminology in the field of nucleic acid folding studies. Readers might like to note that the author's three terms TFE, CFE and FFE(PFE) are very close to those introduced by Le & Maizel in 1989 (E, Er, and E - Er), and by myself in the early 1990s (FONS, FORS-M and FORS-D). For example, see Table 1 of Forsdyke (2007), which may be accessed at BMC.1. Le S-Y, Maizel JV: A method for assessing the statistical significance of RNA folding. J Theor Biol 1989 138:495-510.2 Forsdyke DR: Calculation of folding energies of single-stranded nucleic acid sequences: conceptual issues.J Theor Biol 2007 248:745-753. Competing interests No competing interest.