Figure 9

Selective versus global circumstantial context analysis at the example of actual data. (A) The Kullback-Leibler divergence measures were once calculated for the 899 p53 sensitive probes in the B+ case, and once using the B- probability profiles compared to the B+ biological condition. (B) Data for (A) as in (Figure 8B, D, F). Both tables can be directly compared. (C) Histogram of the Kullback-Leibler divergence distribution over the entire set of 31710 probes analyzed in the two indicated cases. Note that "C1mix" refers to the swapping experiment as illustrated in (Figure 8E). Note also that the final bin encompasses the interval]1..+∞[. (D) Similar histogram as in (C) for the 899 probes showing significant p53 regulation (compare (A)).