From: Construction and analysis of a modular model of caspase activation in apoptosis
Initial concentration (nM) | ||||
---|---|---|---|---|
Species | HeLa | Jurkat T | Parameter | Value |
Casp8 | 216.67 [65] | 33.33 [70, 71] | [FasL]0 | 2 nM [70, 71] |
Casp3 | 35 [65] | 200 [70, 71] | [FasR]0 | 10 nM [70, 71] |
XIAP | 66.67 [65] | 30 [70, 71] | K DISC | 1.032 nM [70, 71] |
BAR | 66.67 [65] | 66.67 [65] | [Bax]0 | 83.33 nM [70, 71] |
Bid | 25 [70, 71] | 25 [70, 71] | 100 nM [70, 71] | |
Cytc | 100 [70, 71] | 100 [70, 71] | [Apaf]0 | 100 nM [70, 71] |
Smac | 100 [70, 71] | 100 [70, 71] | λ Apop | 1 [75] |
Casp9 | 20 [70, 71] | 20 [70, 71] |