Table 3 Comparison of CHD controller functions to DHD controller functions

Track Index

Unknown (possibly enhancers)

Servo Wedge alignment information

Gene promoter regions such as the TATA, Inr and DPE sites and transcription factors accurately aligning the Basal Transcription complex to the gene/sector.

Read Head (Servo Head)

RNA Polymerase II (eukaryote)

Synchronization of servo head to read data (located in header)

Synchronization of RNA Polymerase II to initiation start site by proper alignment to the promoter site by transcription factors. This allows conformational alignment of RNA Polymerase II to transcription start site (part of biological header complex)

Identification of active sectors (header)

Implementation of the histone code. In addition, regulatory elements as well as other possible non coding RNA's influence RNA Polymerase II. (Part of biological header)

Read/Write data acquisition is through rotation of disk platter relative to servo head.

RSC chromatin remolding Complex unwinding DNA double helix in conjunction with RNA Polymerase II (read head) moving step wise along the DNA strand.

Data buffer and sector editing

Sub sector editing/multiplexing of both exons and sectors implemented by splicosomes and wetware circuitry of the DHD controller. This machinery reconstructs the requesting genomic information and its derivatives (including transgenes and isoforms) resulting in a mature mRNA residing in the buffer region of the nucleus.

Bios

Bio-BIOS consisting of transduction circuitry resulting in pathways responsible for translating cellular requests into the RNA regulatory language of the DHD.