Figure 2

Fraction of bound proteins (pure initial state). Does response curves for the system prepared in a pure state: $〈L_0^2〉=L_0^2$ and $〈P_0^2〉=P_0^2$ The curves were obtained in the same way as for Fig. 1. The thickest full line is the reference Hill curve obtained with K = 1. Other curves describe the effects of fluctuations and were obtained using the PARNES method: the full (P₀ = 2), the dashed (P₀ = 3), the dotted (P₀ = 4), and the dot-dash (P₀ = 8). The thinner curves approach the reference mean field curve for large values of P₀. The curves are distinct and their shape depends on the value of P₀.