Figure 4
From: Modeling CICR in rat ventricular myocytes: voltage clamp studies
Calcium channel dynamics. Figure 4: Calcium channel dynamics. (a) Markovian model describing the DHP-sensitive Ca2+ channel, and (b) Markovian model of the Ry-sensitive Ca2+ channel and the luminal SR Ca2+ sensor. Input from the luminal SR Ca2+ sensor modulates the rate constants in the model of Ry-sensitive channel exercising the indirect bias of luminal [Ca2+] jSR on the RyR receptor.