Modeling CICR in rat ventricular myocytes: voltage clamp studies

Table 1 Surface area of various plasma membranes in the cell

Variable	Description	Value
A _Ext.SL	Surface area of external SL	11.4 × 10³ μm²
A _TT	Surface area of T-tubule	5.52 × 10³ μm²
A _TotSL	Surface area of total SL (including external SL and T-tubule)	16.9 × 10³ μm² (*)
A _JunctExt.SL	Surface area of junctional external SL	0.846 × 10³ μm²
A _JunctTT	Surface area of junctional T-tubule	2.54 × 10³ μm²
A _TotJunct	Surface area of total junctional plasma membrane	3.39 × 10³ μm²
A _JunctSR	Surface area of junctional SR	6.99 × 10³ μm²
A _LongSR	Surface area of longitudinal SR	36.8 × 10³ μm²
A _TotSR	Surface area of total SR	43.8 × 10³ μm²

*Electrical capacitance of the cell membrane = 169 pF (using 1 μ F/cm²)
Table 1: Surface area of various plasma membranes in the cell. All the above parameters are derived from Bers [16].

ISSN: 1742-4682