Theoretical Biology and Medical Modelling

Table 10 PPV and sensitivity results for all the different pathways (A - G) run using BANJO and ARACNE

From: Insights gained from the reverse engineering of gene networks in keloid fibroblasts

	A				B
	ARACNE		BANJO		ARACNE		BANJO
	PPV	Se	PPV	Se	PPV	Se	PPV	Se
Keloid RMA	0.238	0.556	0.3	0.667	0.6	1	0.4	0.667
Normal RMA	0.1875	0.333	0.3125	0.556	0.5	0.667	0.4	0.667
Keloid MAS5	0.214	0.333	0.286	0.667	0.5	0.667	0.75	1
Normal MAS5	0.25	0.667	0.304	0.778	0.75	1	0.6	1
Random	0.389				0.5
	C				D
	ARACNE		BANJO		ARACNE		BANJO
	PPV	Se	PPV	Se	PPV	Se	PPV	Se
Keloid RMA	0.8	1	0.75	0.75	0.5	0.6	0.5	0.8
Normal RMA	1	0.75	0.8	1	0.5	0.6	0.2	0.2
Keloid MAS5	0.5	0.25	0.6	0.75	0.5	0.6	0.625	1
Normal MAS5	0.667	0.5	0.5	0.5	0.333	0.4	0.5	0.8
Random	0.667				0.5
	E				F
	ARACNE		BANJO		ARACNE		BANJO
	PPV	Se	PPV	Se	PPV	Se	PPV	Se
Keloid RMA	0.375	0.6	0.364	0.8	0.375	0.75	0.5	1
Normal RMA	0.444	0.8	0.444	0.8	0.5	0.75	0.5	1
Keloid MAS5	0.286	0.4	0.273	0.6	0.286	0.5	0.429	0.75
Normal MAS5	0.333	0.6	0.364	0.8	0.2	0.25	0.429	0.75
Random	0.333				0.4
	G
	ARACNE		BANJO
	PPV	Se	PPV	Se
Keloid RMA	0.5	0.5	0.714	0.833
Normal RMA	0.667	0.667	0.625	0.833
Keloid MAS5	0.4	0.333	0.429	0.5
Normal MAS5	0.833	0.833	0.5	0.5
Random	0.6

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